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Merck - 344827-10MG - Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose | Calbiochem | 10 MG

  • MFR SKU: 344827-10MG
  • ITEM #: 11592098
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$486.50
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ITEM #: 11592098
2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
This listing is for 10 mg Glass bottle

Merck - 344827-10MG - Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose | Calbiochem | 10 MG

  • Item #: 11592098
  • MFR SKU: 344827-10MG
  • Overview A cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic. Treatment of HL-60 cells with this inhibitor shows complete abolition of Lewis-X and SLex within 3 days. Also abolishes P-selectin binding and exhibits faster rolling cells on E-selectin and P-selectin coated surfaces. Does not affect cell viability or their doubling time even at 200 µ M levels.
  • Catalogue Number 344827
  • Brand Family Calbiochem®
  • Synonyms (3S, 4R, 5R, 6S)-3-fluoro-6-methyltetrahydro-2H-pyran-2, 4, 5-triyl triacetate
  • References Rillahan, C., et al. 2012.. Nat. Chem. Bio. 8, 661.
  • Form White solid
  • Hill Formula CHFO
  • Chemical formula CHFO
  • Reversible Y
  • Structure formula Image
  • Quality Level MQ200
  • Primary Target Fucosyltransferase
  • Purity ≥ 98% by NMR
  • Cell permeable Y
  • Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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