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Merck - 345752-1MG - Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk | Calbiochem | 1MG

  • MFR SKU: 345752-1MG
  • ITEM #: 3450051
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ITEM #: 3450051
Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk^ 1mg. White solid. Disrupts mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. . Purity: >=98% by TLC. M.W. 1577.0 (based on tricosanoyl - 23:0).
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Merck - 345752-1MG - Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk | Calbiochem | 1MG

  • Item #: 3450051
  • MFR SKU: 345752-1MG
  • Overview Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD 3 can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).
  • Catalogue Number 345752
  • Brand Family Calbiochem®
  • Synonyms Neu5Acα 2, 8Neu5Acα 2, 3Galβ 1, 4Glcβ 1, 1 Ceramide, 2NH
  • References DeMaria, R., et al. 1997. Science 277, 1652.
  • Form White solid
  • Hill Formula CHNO · 2NH
  • Chemical formula CHNO · 2NH
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 98% by TLC
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to months at -20° C.

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