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Merck - 368020-25MG - Gramicidin A, High Purity, Bacillus brevis - CAS 11029-61-1 - Calbiochem

  • MFR SKU: 368020-25MG
  • ITEM #: 4147854
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ITEM #: 4147854
Gramicidin A, High Purity, Bacillus brevis^ (gA; OHC-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH). Off-white solid. Naturally-occurring ion channel-forming pentadecapeptide. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner.
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Merck - 368020-25MG - Gramicidin A, High Purity, <i>Bacillus brevis</i> - CAS 11029-61-1 - Calbiochem

  • Item #: 4147854
  • MFR SKU: 368020-25MG
  • Overview Naturally-occurring ion channel-forming pentadecapeptide. The association of two gA peptides causes the formation of a monovalent cation-selective ion channel. Causes K + /H + exchange in mitochondria in a non-voltage dependent manner. Causes red blood cell lysis at 0.5-1.0 µg/ml.
  • Catalogue Number 368020
  • Brand Family Calbiochem®
  • Synonyms gA
  • References Quigley, E.P., et al. 2000. J. Membr. Biol. 174, 207.
  • Koeppe, R.E., et al. 1995. Biochemistry 34, 9299.
  • Ketchem, R.R., et al. 1993. Science 261, 1457.
  • Stankovic, C.J., et al. 1990. Anal. Biochem. 184, 100.
  • CAS number 11029-61-1
  • ATP Competitive N
  • Form White to off-white solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Reversible N
  • Quality Level MQ100
  • Primary Target Causes the formation of a monovalent cation-selective ion channel
  • Purity ≥ 90% by HPLC
  • Cell permeable N
  • Contaminants gC isomers: < 5% by HPLC
  • Peptide Sequence HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCHCHOH
  • RTECS MD8230000
  • R Phrase R: 20/21/22-36/37/38
  • Harmful by inhalation, in contact with skin and if swallowed.
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following recosntituion, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.

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