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Merck - 370625-100MG - Guanabenz Acetate | CAS 23256-50-0 | Calbiochem | 100 MG

  • MFR SKU: 370625-100MG
  • ITEM #: 11575145
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ITEM #: 11575145
A cell-permeable α2-adrenoceptor agonist that lowers protein misfolding in stressed cells and acts as a proteostatis regulator.
This listing is for 250 mg Glass bottle

Merck - 370625-100MG - Guanabenz Acetate | CAS 23256-50-0 | Calbiochem | 100 MG

  • Item #: 11575145
  • MFR SKU: 370625-100MG
  • Overview A cell-permeable α 2-adrenoceptor agonist that lowers protein misfolding in stressed cells (EC 50 ~ 400 nM in tunicamycin treated HeLa cells) and acts as a proteostatis regulator. Shown to selectively bind PPP1R15A/GADD34 and disrupt the PPP1R15A-PP1c complex; sustain eIF2α phosphorylation and increase chaperone availability by attenuating translation.
  • Catalogue Number 370625
  • Brand Family Calbiochem®
  • Synonyms 1-(2, 6-Dichlorobenzylideneamino)guanidine, Acetate, WY-8678
  • References Tsaytler, P., et al. 2011. Science 332, 91.
  • Erb, S., et al. 2000. Neuropsychopharmacology 23, 138,
  • Handley, S.L. and Mithani, S., 1984. Naunyn Schmiedebergs Arch. Pharmacol. 327, 1.
  • CAS number 23256-50-0
  • Form White powder
  • Hill Formula CHClN • CHO
  • Chemical formula CHClN • CHO
  • Hygroscopic Hygroscopic
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 99% by HPLC
  • Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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