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Merck - 371822-25MG - GPR120 Agonist III | Calbiochem | 25 MG

  • MFR SKU: 371822-25MG
  • ITEM #: 11575152
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ITEM #: 11575152
The GPR120 Agonist III controls the biological activity of GPR120. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
This listing is for 25 mg Glass bottle

Merck - 371822-25MG - GPR120 Agonist III | Calbiochem | 25 MG

  • Item #: 11575152
  • MFR SKU: 371822-25MG
  • Overview A membrane-permeant biphenyl-methoxy-phenylpropanoate compound that acts as an active-site targeting, selective, potent agonist of G-protein coupled receptor 120/GPR120 (EC 50 of β-arrestin 2 recruitment = 17 nM and 44 nM for mGPR120 and hGPR120, respectively; EC 50 of Ca ++ mobilization = 96 nM for hGPR120). Exhibits much reduced potency toward free fatty acid receptor 1/FFA1/GPR40 (EC 50 of β-arrestin 2 recruitment = 64.6 µ M) and no activity toward short chain FFA receptors FFA2/GPR43 and FFA3/GPR41.
  • Catalogue Number 371822
  • Brand Family Calbiochem®
  • Synonyms 3-(4-((4-Fluoro-4-methyl-(1, 1-biphenyl)-2-yl)methoxy)-phenyl)propanoic acid
  • References Shimpukade, B., et al. 2012. J. Med. Chem. 55, 4511.
  • Form White powder
  • Hill Formula CHFO
  • Reversible Y
  • Quality Level MQ100
  • Primary Target G-protein coupled receptor 120
  • Purity ≥ 97% by HPLC
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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