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Merck - 3779-1GM - Histamine, Free Base | CAS 51-45-6 | Calbiochem | 1GM

  • MFR SKU: 3779-1GM
  • ITEM #: 6280579
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ITEM #: 6280579
Histamine, Free Base^ [2-(4-Imidazolyl)ethylamine]. Potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Purity: >99% by TLC. Soluble in water. CAS: 51-45-6. FW: 111.2. Off-white solid, 1g.
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Merck - 3779-1GM - Histamine, Free Base | CAS 51-45-6 | Calbiochem | 1GM

  • Item #: 6280579
  • MFR SKU: 3779-1GM
  • Overview A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H 1 receptors leads to Ca 2+ mobilization, whereas histamine H 2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells.
  • Catalogue Number 3779
  • Brand Family Calbiochem®
  • Synonyms 2-(4-Imidazolyl)ethylamine
  • References Robinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol. 133, 178.
  • Izumi, H., et al. 1995. Am. J. Obstet. Gynecol. 172, 1477.
  • Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem. 269, 9952.
  • Yan, Q.Z., et al. 1994. Agents Actions 41, C111.
  • Moncada, S., et al. 1991. Pharmacol. Rev . 43, 109.
  • Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York.
  • CAS number 51-45-6
  • Form White solid
  • Hill Formula CHN
  • Chemical formula CHN
  • Hygroscopic Hygroscopic
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 97% by TLC
  • RTECS MS1050000
  • R Phrase R: 22-36/37/38-42/43
  • Harmful if swallowed.
  • Irritating to eyes, respiratory system and skin.
  • May cause sensitization by inhalation and skin contact.
  • S Phrase S: 26-36/37-22
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing and gloves.
  • Do not breathe dust.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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