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Merck - 400051-1MU - Hygromycin B, Streptomyces sp. - CAS 31282-04-9 - Calbiochem

MFR SKU: 400051-1MU

ITEM #: 3441677

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ITEM #: 3441677
Hygromycin B^ Aqueous solution. Unique aminoglycoside antibiotic that inhibits the growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. 1MU.
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Merck - 400051-1MU - Hygromycin B, <i>Streptomyces</i> sp. - CAS 31282-04-9 - Calbiochem

Item #: 3441677

MFR SKU: 400051-1MU

Technical Specs

Overview Unique aminoglycoside antibiotic that inhibits the growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. Hph , a gene from E. coli, encodes resistance to hygromycin B and can be isolated and cloned by recombinant DNA techniques. This hygromycin B-resistance gene is particularly useful for identification or selection of recombinant clones in a variety of cell types. Hygromycin B penetrates cells that have been permeabilized by virus infection and can act as an effective antiviral agent.
Bioassay: 350-450 units/mg Hygromycin B. 10 6 units is equivalent to ~900 mg.
Supplied with a directional insert. Note: 1 KU = 1000 units; 1 MU = 1, 000, 000 units.
Catalogue Number 400051
Brand Family Calbiochem®
References Dean, N. 1995. Proc. Natl. Acad. Sci. USA 92, 1287.
Hamada, W., et al. 1994. Curr. Genetics 26, 251.
Hubbard, S. C., et al. 1994. J. Biol. Chem. 269, 3717.
Rikkerink, E. H., et al. 1994. Current Genetics 25, 202.
Sugimoto, K., et al. 1994. Plant J. 5, 863.
Buchschacher, G.L., Jr., and Panganiban, A.T. 1992. J. Virol. 66, 2731.
Gaken, J., et al. 1992. Biotechniques 13, 32.
Lama, J., and Carrasco, L. 1992. J. Biol. Chem . 267, 15932.
Ma, H., et al. 1992. Gene 117, 161.
MacIntyre, G., et al. 1992. Adv. Exp. Med. Biol. 276, 67.
Norman, J.A., et al. 1992. Mol. Pharmacol. 41, 53.
Bilang, R., et al. 1991. Gene 100, 247.
Dale, E., and Ow, D. 1991. Proc. Natl. Acad. Sci. USA 88, 10558.
Lee, M.G-S., and Van der Ploeg, L. 1991. Gene 105, 255.
Leslie, J.F., and Dickman, M.B. 1991. Applied Environ. Microbiol. 57, 1423.
MacIntyre, G., et al. 1991. Antimicrob. Agents Chemother. 35, 2125.
Zhou, J., et al. 1991. Gene 107, 307.
Bulte, L., and Bennoun, P. 1990. Current Genetics 18, 155.
Giordano, T.J., and McAllister, W.T. 1990. Gene 88, 285.
Salauze, D., et al. 1990. Antimicrob. Agents Chemother. 24, 1915.
Carrasco, L., et al. 1989. Pharmacol. Ther. 9, 311.
Crespi, C.L., et al. 1989. Carcinogenesis 10, 295.
Damm, B., et al. 1989. Mol. Gen. Genetics 217, 6.
Egelhoff, T.T., et al. 1989. Mol. Cell. Biol. 9, 1965.
Kronstad, J.W., et al. 1989. Gene 79, 97.
Perlin, D.S., et al. 1988. J. Biol. Chem. 263, 118.
Cullen, D., et al. 1987. Gene 57, 21.
Gonzalez, A., et al. 1978. Biochim. Biophys. Acta 521, 459.

Malpartida, F., et al. 1983. Biochem. Biophys. Res. Commun. 117, 6.
Rao, S.N., et al. 1983. Antimicrob. Agents Chemother. 24, 689.
CAS number 31282-04-9
Form Amber to brown liquid
Hill Formula CHNO
Chemical formula CHNO
Structure formula Image
Quality Level MQ100
Biological activity The activity of Hygromycin B is measured in a zonal inhibition assay using Bacillus subtilis . The activity is measured relative to a reference standard.
Primary Target growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells
Secondary target protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA
Purity >85% by HPLC
RTECS WK2130000
R Phrase R: 26/27/28-37/38-41
Very toxic by inhalation, in contact with skin and if swallowed.
Irritating to respiratory system and skin.
Risk of serious damage to eyes.
S Phrase S: 23-26-36/37/39-45
Do not breathe fumes.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2° C to +8° C
Do not freeze Ok to freeze
Special Instructions Aqueous stock solutions should be kept at concentrations of ≥ 50 mg/ml and can be stored at either 4° C or -20° C. Aqueous stock solutions (≥ 50 mg/ml) are stable for up to 6 months at 4° C or -20° C. Working solutions (< 2 mg/ml) are stable for up to 1 month at 4° C.
Note: This product is highly toxic. Read enclosed MSDS before handling.

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