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Merck - 401002-10UG - Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem

  • MFR SKU: 401002-10UG
  • ITEM #: 7010233
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ITEM #: 7010233
Iberiotoxin, Buthus tamulus, Recombinant, E. coli
| CAS 129203-60-7 | Calbiochem | 10UG
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Merck - 401002-10UG - Iberiotoxin, <i>Buthus tamulus, </i> Recombinant, <i>E. coli</i> - CAS 129203-60-7 - Calbiochem

  • Item #: 7010233
  • MFR SKU: 401002-10UG
  • Overview Recombinant Buthus tamulus iberiotoxin expressed in E. coli . Acts as a selective, reversible blocker of high conductance Ca 2+ -activated K + channels (IC 50 = 250 pM).
  • Catalogue Number 401002
  • Brand Family Calbiochem®
  • Synonyms rlbTx, Pyr-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
  • References Vanelli, G., et al. 1994. J. Appl. Physiol. 76, 1098.
  • Garcia, M.L., et al. 1991. J. Bioeng. Biomembr. 23, 615.
  • Galvez, A., et al. 1990. J. Biol. Chem. 265, 11083.
  • CAS number 129203-60-7
  • ATP Competitive N
  • Form Salt-free lyophilized solid
  • Reversible Y
  • Quality Level MQ100
  • Biological activity potently inhibits Ca 2+ -activated K + channels expressed in Xenopus oocytes
  • Primary Target High conductance Ca2+-activated K+ channels 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 250 pM against high conductance Ca2+-activated K+ channels
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Peptide Sequence Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys¹³-Trp-Ser-Val-Cys¹-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys²-Met-Gly-Lys-Lys-Cys³³-Arg-Cys³-Tyr-Gln-OH (disulfide bonds: 7 → 28; 13 → 35; 17 → 33)
  • R Phrase R: 20/21/22
  • Harmful by inhalation, in contact with skin and if swallowed.
  • S Phrase S: 36
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C) for long-term storage or refrigerate (4° C) for short-term storage. Stock solutions are stable for up to 3 months at -20° C or up to 2 weeks at 4° C.

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