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Merck - 407293-100KU - -Interferon, Mouse, Recombinant, E. coli

  • MFR SKU: 407293-100KU
  • ITEM #: 3441415
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ITEM #: 3441415
a-Interferon, Mouse, Recombinant, E. coli^ (rmlFN-a). Liquid. In PBS containing 0.1% BSA. Antiviral, antineoplastic agent. Suppresses bone marrow function and induces apoptotic cell death in non-melanoma skin cancer. Activity: 3.5 x 104 units/ml.
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Merck - 407293-100KU - -Interferon, Mouse, Recombinant, <i> E. coli</i>

  • Item #: 3441415
  • MFR SKU: 407293-100KU
  • Overview Recombinant, mouse α-interferon expressed in E. coli . Antiviral and anti-neoplastic agent. Suppresses bone marrow function and induces apoptotic cell death in non-melanoma skin cancer. IFN-α signaling is mediated by JAK1 and TYK2 tyrosine kinases. Note: 1 KU = 1000 units.
  • Catalogue Number 407293
  • Brand Family Calbiochem®
  • References Krishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
  • Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer 61, 110.
  • Dianzani, F. 1993. Gut 34, 574.
  • Brouty-Boyce, D., and Zetter, B.R. 1990. Science 208, 516.
  • Sidky, Y.A., and Borden, E.C. 1987. Cancer Res. 47, 5155.
  • Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol. 119, 34.
  • Pestka, S. 1986. Methods Enzymol. 119, 14.
  • Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.
  • Johnson, M.D., et al. 1981. Methods Enzymol. 78, 394.
  • Rubinstein, S., et al. 1981. J. Virol. 37, 755.
  • Activity ≥ 3.5 x 10 units/ml
  • Unit of Definition One unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.
  • Form Liquid
  • Formulation In PBS containing 0.1% BSA.
  • Quality Level MQ100
  • Purity ≥ 95% by SDS-PAGE
  • Ship Code Dry Ice Only
  • Toxicity Standard Handling
  • Storage ≤ -70° C
  • Avoid freeze/thaw Avoid freeze/thaw
  • Do not freeze Ok to freeze
  • Special Instructions Following initial thaw, aliquot and freeze (-70° C).

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