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Merck - 407950-10MG - Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem

  • MFR SKU: 407950-10MG
  • ITEM #: 5842711
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ITEM #: 5842711
Ionomycin, Free Acid, Streptomyces conglobatus^ Pale-yellow oil. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Highly specific for divalent cations and more effective than antibiotic A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5.
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Merck - 407950-10MG - Ionomycin, Free Acid, <i>Streptomyces conglobatus</i> - CAS 56092-81-0 - Calbiochem

  • Item #: 5842711
  • MFR SKU: 407950-10MG
  • Overview Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105 ) as a mobile ion carrier for Ca 2+ . Complexes with Ca 2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca 2+ transport across biological membranes and measurement of cytoplasmic free Ca 2+ . Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G 1 phase in mature Burkitt lymphoma cell lines.
  • Absorption max. (280 nm, MeOH): 18, 600 M -1 cm -1 .
  • Catalogue Number 407950
  • Brand Family Calbiochem®
  • References Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
  • Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
  • Dupuy d’ Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
  • Lee, H.C. 1993. J. Biol. Chem. 268, 293.
  • Kuznetsov, G., et al. 1992. J. Biol. Chem . 267, 3932.
  • Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
  • Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
  • CAS number 56092-81-0
  • ATP Competitive N
  • Form Waxy solid
  • Hill Formula CHO
  • Chemical formula CHO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Application Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+.
  • Primary Target Mobile ion carrier for Ca2+
  • Purity ≥ 90% by HPLC
  • Cell permeable N
  • RTECS NO0600000
  • R Phrase R: 22
  • Harmful if swallowed.
  • S Phrase S: 36
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, store in the refrigerator (4° C). Stock solutions are stable for up to 1 year at 4° C.
  • Packaged under inert gas Packaged under inert gas

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