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Merck - 420600-50MG - Ketoconazole | CAS 65277-42-1 | Calbiochem | 50MG

  • MFR SKU: 420600-50MG
  • ITEM #: 6280834
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ITEM #: 6280834
An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities.
This listing is for 50 mg Glass bottle

Merck - 420600-50MG - Ketoconazole | CAS 65277-42-1 | Calbiochem | 50MG

  • Item #: 6280834
  • MFR SKU: 420600-50MG
  • Overview An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC 50 = 26 µ M) and thromboxane synthase activities.
  • Catalogue Number 420600
  • Brand Family Calbiochem®
  • Synonyms cis -1-Acetyl-4-[4-[[2-(2, 4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1, 3-dioxolan-4-yl]methoxy]phenyl]piperazine, R-41400, CYP17A1 Inhibitor I
  • References van Wauwe, J.P., and Janssen, P.A.J. 1989. J. Med. Chem. 32, 2231.
  • Beetens, J.R., et al. 1986. Biochem. Pharmacol. 35, 883.
  • Lambert, A., et al. 1986. Biochem. Pharmacol. 35, 3999.
  • Tucker, W.F.G., and MacNeil, S. 1986. Br. Med. J. 293, 882.
  • Lelcuk, S., et al. 1984. J. Trauma 24, 393.
  • CAS number 65277-42-1
  • Form Off-white solid
  • Hill Formula CHClNO
  • Chemical formula CHClNO
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target 5-LO 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 26 µ M
  • Purity ≥ 98% by HPLC
  • RTECS TK7912300
  • R Phrase R: 25-40-63-36/37/38
  • Toxic if swallowed.
  • Limited evidence of a carcinogenic effect.
  • Possible risk of harm to the unborn child.
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 22-26-36
  • Do not breathe dust.
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Toxic & Carcinogenic / Teratogenic
  • Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
  • Storage +2° C to +8° C
  • Do not freeze Ok to freeze

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