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Merck - 437725-25UG - Lipoxin A, 15-epi - CAS 171030-11-8 - Calbiochem

  • MFR SKU: 437725-25UG
  • ITEM #: 19011218
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ITEM #: 19011218
Lipoxin A, 15-epi, CAS 171030-11-8, is an epimeric lipoxin A4 (Cat. No. 437720) analog that is more potent and metabolically stable than LXA4.
This listing is for 25 μg Glass bottle

Merck - 437725-25UG - Lipoxin A, 15-epi - CAS 171030-11-8 - Calbiochem

  • Item #: 19011218
  • MFR SKU: 437725-25UG
  • Overview A epimeric lipoxin A 4 (Cat. No. 437720 ) analog that is more potent and metabolically stable than LXA 4 . Exhibits anti-inflammatory properties and serves as a "stop signal" to excessive leukocyte trafficking/infiltration. Blocks TNF-α-induced IL-8 release in human enterocyte. It is also an important modulator of the many pharmacological actions caused by aspirin.
  • Caution! Product contains volatile liquid. Keep product cold at all times.
  • Catalogue Number 437725
  • Brand Family Calbiochem®
  • Synonyms LXA-15-epi, 15( R )-LXA, Aspirin-triggered LXA, (5 S , 6 R , 15 R )-5, 6, 15-Trihydroxy-7, 9, 13- trans -11- cis -eicosatetraenoic acid
  • References Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323.
  • Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223.
  • Titos, E., et al. 1999. Am. J. Physiol. 277, C870.
  • Gronert, K., et al. 1998. J. Exp. Med. 187, 1285.
  • Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972.
  • Claria, J., et al. 1996. Mol. Med. 2, 583.
  • Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475.
  • Serhan, C.N., et al. 1995. Biochemistry 34, 14609.
  • CAS number 171030-11-8
  • ATP Competitive N
  • Form Liquid
  • Formulation In Ethanol.
  • Hill Formula CHO
  • Chemical formula CHO
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Exhibits anti-inflammatory properties
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Ship Code Dry Ice Only
  • Toxicity Flammable
  • Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
  • Storage ≤ -70° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following initial thaw aliquot and freeze (-70° C).
  • Packaged under inert gas Packaged under inert gas

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