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Merck - 440025-5MG - Luteolin | CAS 491-70-3 | Calbiochem | 5MG

  • MFR SKU: 440025-5MG
  • ITEM #: 3441913
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ITEM #: 3441913
Luteolin^ (3', 4', 5, 7-Tetrahydroxyflavone) Antioxidant flavonoid and free radical scavenger. Inhibits rat liver cytosolic glutathione S-transferase activity. Cytotoxic to Raji lymphoma cells. Purity: >=95% by TLC. Soluble in aqueous alkaline solutions. CAS: 491-70-3. FW: 286.2. Yellow solid, 5mg.
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Merck - 440025-5MG - Luteolin | CAS 491-70-3 | Calbiochem | 5MG

  • Item #: 3441913
  • MFR SKU: 440025-5MG
  • Overview An antioxidant flavonoid and a free radical scavenger. Inhibits rat liver cytosolic glutathione S-transferase activity. Also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T½ CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G 2 /M phase of the cell cycle. Also shown to inhibit TPL2 kinase.
  • Catalogue Number 440025
  • Brand Family Calbiochem®
  • Synonyms 3, 4, 5, 7-Tetrahydroxyflavone
  • References Kim, J.E., et al. 2011. J. Pharmacol. Exp. Ther. in press.
  • Korkina, L.G., and Afanasev, I.B. 1997. Adv. Pharmacol. 38, 151.
  • Plaumann, B., et al. 1996. Oncogene 13, 1605.
  • Ramanathan, R., et al. 1994. Free Radic. Biol. Med. 16, 43.
  • Shimoi, L., et al. 1994. Carcinogenesis 15, 2669.
  • CAS number 491-70-3
  • ATP Competitive N
  • Form Yellow solid
  • Hill Formula CHO
  • Chemical formula CHO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target rat liver cytosolic glutathione S-transferase activity
  • Purity ≥ 90% by HPLC
  • Cell permeable N
  • RTECS LK9275210
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 4 weeks at -20° C.
  • Packaged under inert gas Packaged under inert gas

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