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Merck - 444258-1MG - MMP-14 Substrate I, Fluorogenic (MMP14) | Calbiochem | 1MG

  • MFR SKU: 444258-1MG
  • ITEM #: 3450284
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ITEM #: 3450284
MMP-14 Substrate I, Fluorogenic^ 1mg. MCA-PLA-C(OMeBz)-WAR(Dpa)-NH2. MT1-MMP Substrate I, Fluorogenic. White to yellow lyophilized solid. Fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. Purity:>=97% HPLC. Excitation max~328 nm; emission max~400 nm.
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Merck - 444258-1MG - MMP-14 Substrate I, Fluorogenic (MMP14) | Calbiochem | 1MG

  • Item #: 3450284
  • MFR SKU: 444258-1MG
  • Overview A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. (k cat /K m = 7.3 x 10 5 M -1 s -1 for MMP-14 (MT1-MMP) and 3.6 x 10 4 M -1 s -1 for MMP-11 at 25° C, pH 7.5).
  • Catalogue Number 444258
  • Brand Family Calbiochem®
  • Synonyms MCA-PLA-C(OMeBz)-WAR(Dpa)-NH, MT1-MMP Substrate I, Fluorogenic
  • References Mucha, A., et al. 1998. J. Biol. Chem. 273, 2763.
  • ATP Competitive N
  • Form Yellow lyophilized solid
  • Formulation Supplied as a trifluoroacetate salt.
  • Hill Formula CHNOS
  • Chemical formula CHNOS
  • Reversible N
  • Quality Level MQ100
  • Primary Target MMP-14 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> kcat/Km = 7.3 x 105 M-1s-1 for MMP-14; .6 x 104 M-1s-1 for MMP-11
  • Purity ≥ 97% by HPLC
  • Cell permeable N
  • Emission max.
  • Excitation max.
  • Peptide Sequence MCA-Pro-Leu-Ala-Cys( p -OMeBz)-Trp-Ala-Arg(Dpa)-NH Dpa = N³-(2, 4-dinitrophenyl)-L-2, 3-diaminopropionyl, Bz = Benzyl
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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