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Merck - 475872-25MG - MnTMPyP | Calbiochem | 25MG

  • MFR SKU: 475872-25MG
  • ITEM #: 3441487
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ITEM #: 3441487
MnTMPyP^ [Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin pentachloride]. Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2-superoxide even in the presence of excess EDTA. Purity: >=95% by TLC. Soluble in water. FW: 909.0. Brown solid, 25mg.
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Merck - 475872-25MG - MnTMPyP | Calbiochem | 25MG

  • Item #: 3441487
  • MFR SKU: 475872-25MG
  • Overview Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O 2 – • (rate constant ~4 x 10 7 M -1 s -1 ) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O 2 • oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox-coupled with biological antioxidants.
  • Catalogue Number 475872
  • Brand Family Calbiochem®
  • Synonyms Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin, Tetratosylate, Hydroxide
  • References Izbicka, E., et al. 1999. Cancer Res. 59, 639.
  • Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 6053.
  • Gardner, P.R., et al. 1996. Arch. Biochem. Biophys. 325, 20.
  • Liochev, S.I., and Fridovich, I. 1995. Arch. Biochem. Biophys. 321, 271.
  • Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471.
  • ATP Competitive N
  • Form Black solid
  • Hill Formula CHMnNOS
  • Chemical formula CHMnNOS
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Superoxide dismutase (SOD) mimetic
  • Purity ≥ 95% by TLC
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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