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Merck - 484100-10MG - 5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB) | CAS 107254-86-4 | Calbiochem | 10MG

  • MFR SKU: 484100-10MG
  • ITEM #: 6280632
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ITEM #: 6280632
5-Nitro-2-(3-phenylpropylamino)benzoic Acid^ (NPPB). Yellow solid. Potent Cl- channel blocker (IC50 = 100 nM - 100 mM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 mM). Purity: >= 98% by TLC. Soluble in DMSO. CAS 107254-86-4, M.W. 300.3.
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Merck - 484100-10MG - 5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB) | CAS 107254-86-4 | Calbiochem | 10MG

  • Item #: 6280632
  • MFR SKU: 484100-10MG
  • Overview Potent Cl – channel blocker (IC 50 = 100 nM-100 µ M), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC 50 = 8 µ M).
  • Catalogue Number 484100
  • Brand Family Calbiochem®
  • Synonyms NPPB, ANO Blocker II, Anoctamin Blocker II, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II
  • References Illek, B., et al. 1992. Am. J. Physiol. 263, C644.
  • Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
  • Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
  • Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.
  • CAS number 107254-86-4
  • ATP Competitive N
  • Form Yellow solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Cl channel blocker 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 100 nM-100 µ M as Cl-channel blocker
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +15° C to +30° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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