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Merck - 506274-5MG - PACOCF - CAS 141022-99-3 - Calbiochem

  • MFR SKU: 506274-5MG
  • ITEM #: 19012106
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ITEM #: 19012106
PACOCF3^ (Palmitoyl trifluoromethyl ketone). White solid. A novel Ca2+-independent reversible inhibitor of phospholipase A2 (IC50 = 3.8 mM). May also inhibit Ca2+-dependent phospholipase A2 at much higher concentrations (IC50 = 45 mM). Purity: >= 97% by TLC. Soluble in DMSO and EtOH. M.W. 308.4.
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Merck - 506274-5MG - PACOCF - CAS 141022-99-3 - Calbiochem

  • Item #: 19012106
  • MFR SKU: 506274-5MG
  • Overview A novel Ca 2+ -independent and reversible inhibitor of phospholipase A 2 (PLA 2 ; IC 50 = 3.8 µ M). May also inhibit Ca 2+ -dependent PLA 2 at much higher concentrations (IC 50 = 45 µ M).
  • Catalogue Number 506274
  • Brand Family Calbiochem®
  • Synonyms Palmitoyl Trifluoromethyl Ketone
  • References Conde-Frieboes, K., et al. 1996. J. Am. Chem. Soc. 118, 5519.
  • Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
  • Ackermann, E.J., et al. 1995. J. Biol. Chem. 270, 445.
  • CAS number 141022-99-3
  • ATP Competitive N
  • Form Liquid
  • Formulation In ethanol.
  • Hill Formula CHFO
  • Chemical formula CHFO
  • Reversible Y
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target PLA 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 3.8 µ M and 45 µ M against phospholipase A2 (PLA2) and Ca2+-dependent PLA2, respectively.
  • Purity ≥ 97% by TLC
  • Cell permeable N
  • Ship Code Shipped with Blue Ice or with Dry Ice
  • Toxicity Standard Handling
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution in DMSO, aliquot and freeze (-20° C). Stock solutions are stable for up to 1 month at -20° C. Product has a very low melting point. The product will change from a solid to a liquid if held in your hand or kept at room temperature or warmer for any period of time. It is best to keep the product cool while in use by placing it in the refrigerator or on ice during experimentation. Once diluted in buffer, do not store in aqueous solutions for >1 day.

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