Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - 506350-2MG - PamCys-Ser-(Lys), Hydrochloride

  • MFR SKU: 506350-2MG
  • ITEM #: 6310971
  • 0 Reviews / 0 Questions
$696.42
Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 6310971
Pam3Cys-Ser-Lys4 Hcl-2Mg^ Pam3Cys-Ser-(Lys)4, Hydrochloride. Form: Lyophilized solid, Storage: -20DegreeC, purity: =90% by HPLC 2mg
This listing is for Each

Merck - 506350-2MG - PamCys-Ser-(Lys), Hydrochloride

  • Item #: 6310971
  • MFR SKU: 506350-2MG
  • Overview A cell-permeable, water-soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Induces the release of IL-1, IL-6, TNF-α, superoxide, and NO. Promotes the translocation of NF-κ B, enhances tyrosine protein phosphorylation and activation of ERK1/2 and MEK1/2. Acts as a selective agonist of TLR2 (Toll-like receptor 2).
  • Catalogue Number 506350
  • Brand Family Calbiochem®
  • Synonyms (S)-[2, 3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys-OH, 3HCl, PCSK, 3HCl, PamCys-SK, 3HCl, Pam3CSK4, TLR1/TLR2 Agonist I
  • References Barrenschee, M., et al. 2010. PLoS One. 5, e13889.
  • Zahringer, U., et al. 2008. Immunology. 213, 205.
  • Toshchakov, V., et al. 2002. Nat. Immunol. 3, 392.
  • Muller, M.R., et al. 2001. Immunology 103, 49.
  • Vergne, I., and Cezanne, L. 1999. Eur. J. Biochem. 264, 369.
  • Diaz-Guerra, M.J., et al. 1996. J. Biol. Chem. 271, 30114.
  • Offermanns, S., et al. 1992. Biochem. J. 282, 551.
  • Seifert, R., et al. 1990. Biochem. J. 267, 795.
  • Hoffmann, P., et al. 1989. Biol. Chem. Hoppe. Seyler. 370, 575.
  • CAS number 112208-00-1
  • Form Lyophilized solid
  • Hill Formula CHNOS • 3 HCl
  • Chemical formula CHNOS • 3 HCl
  • Quality Level MQ100
  • Purity ≥ 90% by HPLC
  • Ship Code Blue Ice Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Avoid freeze/thaw cycles of solutions.

There are no questions about this product yet. Be the first to ask a question.

0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Recently Viewed Items