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Merck - 524403-25MG - Pravastatin, Sodium Salt | CAS 81131-70-6 | Calbiochem | 25MG

  • MFR SKU: 524403-25MG
  • ITEM #: 19012203
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ITEM #: 19012203
Pravastatin, Sodium Salt^ 25mg. 3 beta -Hydroxycompactin, Na. White solid. Water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis. Purity: >=98% by HPLC. CAS 81131-70-6. Hygroscopic. MW 446.5.
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Merck - 524403-25MG - Pravastatin, Sodium Salt | CAS 81131-70-6 | Calbiochem | 25MG

  • Item #: 19012203
  • MFR SKU: 524403-25MG
  • Overview A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (K i = ~1 nM). Offers cardioprotection. Also acts as an immunomodulator and an inhibitor of ras p21 isoprenylation.
  • Catalogue Number 524403
  • Brand Family Calbiochem®
  • Synonyms (β R, δ R, 1S, 2S, 6S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro-β, δ, 6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic Acid Na, 3β-Hydroxycompactin, Na
  • References Kwak, B., et al. 2000. Natl. Med. 6, 1399.
  • Hamelin, B.A., and Turgeon, J., 1998. Trends Pharmacol. Sci. 19, 26.
  • Narisawa, T., et al. 1996. Jpn. J. Cancer Res. 87, 798.
  • Cohen, L.H., et al. 1993. Biochem. Pharmacol. 45, 2203.
  • Koga, T., et al. 1990. Biochim. Biophys. Acta. 1045, 115.
  • Yoshino, G., et al. 1986. Diabetes Res. Clin. Pract. 2, 179
  • CAS number 81131-70-6
  • ATP Competitive N
  • Form White crystalline solid
  • Hill Formula CHO.Na
  • Chemical formula CHO.Na
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target AMG-CoA reductase i $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target K i " value=" Biological Information"
  • br> Primary Target K<sub>i</sub> ~1 nM inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and blocking in vivo cholesterol synthesis
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • RTECS QJ7185000
  • Ship Code Ambient Temperature Only
  • Toxicity Environmental Hazard
  • Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
  • Storage +2° C to +8° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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