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Merck - 524644-1MG - L-alpha-Phosphatidyl-D-myo-inositol-4, 5-bisphosphate, Triammonium Salt, Porcine Brain | CAS 383907-42-4 | Calbiochem | 1 MG

  • MFR SKU: 524644-1MG
  • ITEM #: 6280475
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ITEM #: 6280475
L-a-Phosphatidyl-D-myo-inositol-4, 5-bisphosphate, Triammonium, Bovine Brain^ (PIP2, ammonium). Off-white solid. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A component of membrane-bound receptors in association with phospholipase C.
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Merck - 524644-1MG - L-alpha-Phosphatidyl-D-myo-inositol-4, 5-bisphosphate, Triammonium Salt, Porcine Brain | CAS 383907-42-4 | Calbiochem | 1 MG

  • Item #: 6280475
  • MFR SKU: 524644-1MG
  • Overview A component of membrane-bound receptors in association with phospholipase C (PLC). Potently stimulates brain phospholipase D (PLD) activity in vitro . Has been shown to activate protein kinase C (PKC) in the presence of phosphatidylserine and Ca 2+ . Antagonist of ATP-sensitive potassium (K ATP ) channels when applied to inside-out membrane patches.
  • Catalogue Number 524644
  • Brand Family Calbiochem®
  • Synonyms PIP
  • References Baukrowitz, T., et al. 1998. Science 282, 1141.
  • Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138.
  • Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181.
  • Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403.
  • Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun . 175, 852.
  • Williamson, J.R. 1986. Hypertension 8, 140.
  • Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.
  • CAS number 383907-42-4
  • ATP Competitive N
  • Form White to off-white solid
  • Hill Formula CHOP · 3NH
  • Chemical formula CHOP · 3NH
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Brain phospholipase D (PLD)
  • Purity ≥ 98% by TLC
  • Cell permeable N
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Dry Ice Only
  • Toxicity Irritant
  • Storage ≤ -70° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution in HO, store in the refrigerator (4° C). Do not freeze aqueous solutions. Following reconstitution in chloroform, aliquot and freeze (-20° C). Aqueous stock solutions are stable for up to 2 days at 4° C. Chloroform stock solutions are stable for up to 1 month at -20° C.
  • Packaged under inert gas Packaged under inert gas

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