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Merck - 528245-5MG - PLD Inhibitor, FIPI | Calbiochem | 5 MG

  • MFR SKU: 528245-5MG
  • ITEM #: 11575783
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$275.00
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ITEM #: 11575783
The PLD Inhibitor, FIPI controls the biological activity of PLD. This small molecule/inhibitor is primarily used for Membrane applications.
This listing is for 5 mg Glass bottle

Merck - 528245-5MG - PLD Inhibitor, FIPI | Calbiochem | 5 MG

  • Item #: 11575783
  • MFR SKU: 528245-5MG
  • Overview A cell-permeable, PLD1/2 inhibitor (IC 50 = 1 nM and 10 nM for PLD1 and PLD2, respectively, in a CHO cell based assay, and IC 50 = 20 nM for PLD2 in a biochemical assay), that displays no activity toward MitoPLD, and is selective for PLD1 and PLD2 over other PLD superfamily enzymes. It is also shown to block PLD2-dependent effects on cytoskeletal reorganization and cell trafficking in CHO cells, and diminish fMLP-directed neutrophil chemotaxis in HL60 cells at 750 nM. Unlike 1-butanol, this compound does not affect glucose-stimulated insulin secretion in Min6 pancreatic β-cells.
  • Catalogue Number 528245
  • Brand Family Calbiochem®
  • Synonyms Compound 4k, PLD Inhibitor I
  • References Su, W., et al. 2009. Mol Pharmacol 75, 437.
  • Monovich, L., et al. 2007. Bioorg Med Chem 17, 2310.
  • Form Off-white powder
  • Hill Formula CHFNO
  • Chemical formula CHFNO
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 99% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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