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Merck - 530050-10MG - PRIMA-1 | CAS 5608-24-2 | Calbiochem | 10 MG

  • MFR SKU: 530050-10MG
  • ITEM #: 4149996
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ITEM #: 4149996
PRIMA-1^ 10mg. 2, 2-Bis(hydroxymethyl)-1-azabicyclo[2, 2, 2]octan-3-one. p53 Reactivation and Induction of Massive Apoptosis. Off-white solid. Hygroscopic. Packaged under inert gas. A cell-permeable quinuclidinone analog with antitumor properties. Purity: >=95% by TLC. MW 185.2.
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Merck - 530050-10MG - PRIMA-1 | CAS 5608-24-2 | Calbiochem | 10 MG

  • Item #: 4149996
  • MFR SKU: 530050-10MG
  • Overview A cell-permeable quinuclidinone analog with antitumor properties. Restores biochemical and biological function to mutant p53 and induces p53-dependent apoptosis in vitro and in vivo . Induces apoptosis in breast cancer cells expressing mutant p53.
  • Catalogue Number 530050
  • Brand Family Calbiochem®
  • Synonyms 2, 2-Bis(hydroxymethyl)-1-azabicyclo[2, 2, 2]octan-3-one, p 53 R eactivation and I nduction of M assive A poptosis
  • References Bykov, V.J., et al. 2002. Nat. Med. 8, 282.
  • CAS number 5608-24-2
  • ATP Competitive N
  • Form Off-white solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Restores biochemical and biological function to mutant p53
  • Purity ≥ 95% by NMR
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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