Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - 553525-25MG - RAD51 Inhibitor, B02 - CAS 1290541-46-6 - Calbiochem

  • MFR SKU: 553525-25MG
  • ITEM #: 11575890
  • 0 Reviews / 0 Questions
$254.00
Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 11575890
The RAD51 Inhibitor, B02 controls the biological activity of RAD51. This small molecule/inhibitor is primarily used for Cell Structure applications.
This listing is for 25 mg Glass bottle

Merck - 553525-25MG - RAD51 Inhibitor, B02 - CAS 1290541-46-6 - Calbiochem

  • Item #: 11575890
  • MFR SKU: 553525-25MG
  • Overview A cell-permeable pyridinylvinyl-quinazolinone compound that is shown to specifically inhibit human RAD51 (IC 50 = 27.4 µ M). Does not affect RecA even at much higher concentration (~250 µ M). Directly interacts with RAD51 (K d = 5.6 µ M), and disrupts its binding to DNA and nucleoprotein filament formation. Blocks double-strand break-induced homologous recombination and enhances sensitivity of cells to Cisplatin ( Cat. No. 232120 ) and Mitomycin C ( Cat. No. 47589), ( Cat. No. 475820 ). Diminishes co-aggregate formation between RAD51-ssDNA filament and dsDNA. RAD51-Stimulatory Compound-1, RS-1 ( Cat. No. 553510 ) is also available.
  • Catalogue Number 553525
  • Brand Family Calbiochem®
  • Synonyms ( E )-3-Benzyl-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one
  • References Huang, F., et al. 2012. J. Med. Chem. 55, 3031.
  • Huang, F., et al. 2011. ACS Chem. Biol. 6, 628.
  • CAS number 1290541-46-6
  • Form Light yellow powder
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 98% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Regulatory Review
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

There are no questions about this product yet. Be the first to ask a question.

0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Recently Viewed Items