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Merck - 554325-25MG - Resveratrol | CAS 501-36-0 | Calbiochem | 25MG

  • MFR SKU: 554325-25MG
  • ITEM #: 3034711
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ITEM #: 3034711
Resveratrol^ (trans-3, 4', 5-Trihydroxystilbene). Phenolic product found in both grape skin and wines. Has antifungal, antitumor and antioxidative properties. Specific inhibitor of cyclooxygenase-1 (ED50=15uM). Purity: >=98% by TLC. Soluble in DMSO. CAS: 501-36-0. FW: 228.2. Off-white solid, 25mg.
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Merck - 554325-25MG - Resveratrol | CAS 501-36-0 | Calbiochem | 25MG

  • Item #: 3034711
  • MFR SKU: 554325-25MG
  • Overview A phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED 50 = 15 µ M). Also inhibits the hydroxyperoxidase activity of COX-1 (ED 50 = 3.7 µ M). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED 50 = 27 µ M) and acts as an anti-mutagenic agent (ED 50 = 15 µ M) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
  • Catalogue Number 554325
  • Brand Family Calbiochem®
  • Synonyms trans -3, 4, 5-Trihydroxystilbene
  • References Howitz, K.T., et al. 2003. Nature 425, 191.
  • Lin, H.Y., et al. 2002. J. Urol. 168, 748.
  • Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312.
  • Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun. 262, 20.
  • Jang, M., et al. 1997. Science 275, 218.
  • Chen, C.K., et al. 1996. Gen. Pharmacol. 27, 363.
  • CAS number 501-36-0
  • ATP Competitive N
  • Form Off-white solid
  • Hill Formula CHO
  • Chemical formula CHO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target COX-1 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> ED50 = 15 µ M against COX-1
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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