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Merck - 554994-10MG - RHC-80267 | CAS 83654-05-1 | Calbiochem | 10 MG

  • MFR SKU: 554994-10MG
  • ITEM #: 4148070
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ITEM #: 4148070
RHC-80267^ ( [1, 6-bis(Cyclohexyloximinocarbonylamino)hexane]). Off-white solid. Selectively inhibits DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets.
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Merck - 554994-10MG - RHC-80267 | CAS 83654-05-1 | Calbiochem | 10 MG

  • Item #: 4148070
  • MFR SKU: 554994-10MG
  • Overview Selective inhibitor of DAG lipase activity in canine platelets (IC 50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II (Cat. No. 05-23-0101 ) and ATP-induced synthesis of 6-keto-prostaglandin F1α.
  • Catalogue Number 554994
  • Brand Family Calbiochem®
  • Synonyms 1, 6- bis (Cyclohexyloximinocarbonylamino)hexane
  • References Shinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295.
  • Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207.
  • Konrad, R.J., et al. 1994. Biochemistry 33, 13284.
  • Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197.
  • Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.
  • CAS number 83654-05-1
  • ATP Competitive N
  • Form White to off-white solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target DAG lipase 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 4 nM against DAG lipase activity in canine platelets
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +15° C to +30° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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