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Merck - 557404-5MG - InSolution RNA Polymerase III Inhibitor | CAS 577784-91-9 | Calbiochem | 5 MG

  • MFR SKU: 557404-5MG
  • ITEM #: 11575908
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ITEM #: 11575908
The InSolution™ RNA Polymerase III Inhibitor, also referenced under CAS 577784-91-9, controls the biological activity of RNA Polymerase III. This small molecule/inhibitor is primarily used for Cell Structure applications.
This listing is for 5 mg Glass bottle

Merck - 557404-5MG - InSolution RNA Polymerase III Inhibitor | CAS 577784-91-9 | Calbiochem | 5 MG

  • Item #: 11575908
  • MFR SKU: 557404-5MG
  • Overview A cell-permeable inhibitor of RNA polymerase III (RNA Pol III) (IC 50 = 27 µ M for human RNA Pol III and 32 µ M for Saccharomyces cerevisiae RNA Pol III). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. The solid form of this compound (Cat. No. 557403 ) is also available.
  • Catalogue Number 557404
  • Brand Family Calbiochem®
  • Synonyms 2-Chloro-N-(3-(5-chloro-3-methylbenzo[b]thiophen-2-yl)-1-methyl-1H-pyrazol-5-yl)benzenesulfonamide, N-(1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl))-2-chlorobenzenesulfonamide
  • References Wu, L., et al. 2003. Euk. Cell 2, 256.
  • CAS number 577784-91-9
  • Form Liquid
  • Formulation A 25 mM (5 mg/442 µ L) solution of RNA Polymerase III Inhibitor (Cat. No. 557403 ) in DMSO.
  • Hill Formula CHClNOS
  • Hygroscopic Hygroscopic
  • Reversible Y
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target RNA Polymerase III 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 27 µ
  • Purity ≥ 97% by HPLC
  • Cell permeable Y
  • R Phrase R: 36/38
  • Irritating to eyes and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Dry Ice Only
  • Toxicity Standard Handling
  • Storage ≤ -70° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Avoid freeze/thaw Avoid freeze/thaw
  • Do not freeze Ok to freeze
  • Special Instructions Following initial thaw, aliquot and freeze (-70° C). Aliquots are stable for up to 6 months at -70° C.
  • Packaged under inert gas Packaged under inert gas

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