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Merck - 567022-5MG - InSolution Simvastatin, Sodium Salt | Calbiochem | 5MG

  • MFR SKU: 567022-5MG
  • ITEM #: 11575939
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ITEM #: 11575939
InSolution™ Simvastatin, Sodium Salt, 101314-97-0, is provided as a 10 mM in HO. It is the carboxylate form of Simvastatin that is active in whole cells and in cell-free preparations.
This listing is for 5 mg Glass bottle

Merck - 567022-5MG - InSolution Simvastatin, Sodium Salt | Calbiochem | 5MG

  • Item #: 11575939
  • MFR SKU: 567022-5MG
  • Overview Carboxylate form of Simvastatin (Cat. No. 567020 ) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca 2+ -signaling and insulin secretion by blocking L-type Ca 2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. The solid form of this compound (Cat. No. 567021 ) is also available.
  • Catalogue Number 567022
  • Brand Family Calbiochem®
  • Synonyms L-Type Calcium Channel Blocker VI
  • References Yada, T., et al. 1999. Br. J. Pharmacol. 126, 1205.
  • Clutterbuck, R.D., et al. 1998. Br. J. Haematol. 102, 522.
  • Yokoyama, K., et al. 1998. Mol. Biochem. Parasitol. 94, 87.
  • Negre-Aminou, P., et al. 1997. Biochim. Biophys. Acta 1345, 259.
  • Vrtovsnik, F., et al. 1997. Kidney Int. 52, 1016.
  • Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.
  • Form Liquid
  • Formulation A 10 mM (5 mg/1.09 ml) solution of Simvastatin, Sodium Salt (Cat. No. 567021 ) in HO.
  • Hill Formula CHO • Na
  • Chemical formula CHO • Na
  • Reversible Y
  • Structure formula Image
  • Quality Level MQ100
  • Application InSolution™ Simvastatin, Sodium Salt, 101314-97-0, is provided as a 10 mM in HO. It is the carboxylate form of Simvastatin that is active in whole cells and in cell-free preparations.
  • Purity ≥ 95% by HPLC
  • Cell permeable Y
  • R Phrase R: 36/38
  • Irritating to eyes and skin.
  • S Phrase S: 26
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Ship Code Dry Ice Only
  • Toxicity Irritant
  • Storage ≤ -70° C
  • Protect from Light Protect from light
  • Avoid freeze/thaw Avoid freeze/thaw
  • Do not freeze Ok to freeze
  • Special Instructions Following initial thaw, aliquot and freeze (-70° C).
  • Packaged under inert gas Packaged under inert gas

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