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Merck - 567430-250MG - Sodium Butyrate (Butyric Acid, Na) | CAS 156-54-7 | Calbiochem | 250MG

  • MFR SKU: 567430-250MG
  • ITEM #: 3040141
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ITEM #: 3040141
Sodium Butyrate^ (Butyric Acid, sodium; NaB). A physiologically produced short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway. Purity: >=98% by titration. Soluble in water. CAS: 156-54-7. White solid, 250mg.
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Merck - 567430-250MG - Sodium Butyrate (Butyric Acid, Na) | CAS 156-54-7 | Calbiochem | 250MG

  • Item #: 3040141
  • MFR SKU: 567430-250MG
  • Overview A short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway. Inhibits c- myc splicing and interferes with signal transduction processes, including the release of Ca 2+ from intracellular stores. Reduces histamine-induced calcium mobilization in C6 glioma cells. Down-regulates the activity of the serine/threonine protein kinase casein kinase II in HT29 cells.
  • Catalogue Number 567430
  • Brand Family Calbiochem®
  • Synonyms Butyric Acid, Na, NaB, HDAC Inhibitor V
  • References Ou, H.C., et al. 1997. Neuroreport 8, 1375.
  • Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
  • Krupitza, G., et al. 1995. Carcinogenesis 16, 1199.
  • Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun. 195, 31.
  • Hague, A., et al. 1993. Int. J. Cancer 55, 498.
  • CAS number 156-54-7
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHONa
  • Chemical formula CHONa
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ200
  • Application Sodium Butyrate, CAS 156-54-7, is a short chain fatty acid that induces apoptosis in colon carcinoma cells by a p53-independent pathway. Down-regulates the activity of casein kinase II in HT29 cells.
  • Primary Target Induce apoptosis
  • Purity ≥ 98% by titration
  • Cell permeable N
  • RTECS ET6400000
  • R Phrase R: 20/21/22-36/37/38
  • Harmful by inhalation, in contact with skin and if swallowed.
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage -20° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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