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Merck - 567616-100MG - Sodium 4-Phenylbutyrate | CAS 1716-12-7 | Calbiochem | 100MG

  • MFR SKU: 567616-100MG
  • ITEM #: 3043021
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ITEM #: 3043021
Sodium 4-Phenylbutyrate^ (SPB; PFNa; 4PBA; 4-phenylbutyrate, Na). A novel anti-neoplastic agent and transcriptional regulator. Inducer of tumor cytostasis and differentiation. Purity: >=98% by titration. Soluble in water. CAS: 1716-12-7. FW: 186.2. White to slightly yellowish solid, 100mg.
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Merck - 567616-100MG - Sodium 4-Phenylbutyrate | CAS 1716-12-7 | Calbiochem | 100MG

  • Item #: 3043021
  • MFR SKU: 567616-100MG
  • Overview A novel anti-neoplastic agent and transcriptional regulator. Also acts as an inducer of tumor cytostasis and differentiation. Increases fetal hemoglobin production in vitro and in vivo .
  • Catalogue Number 567616
  • Brand Family Calbiochem®
  • Synonyms SPB, PBNa, 4PBA, 4-Phenylbutyrate, Na, BDK Inhibitor I, BCKD Kinase Inhibitor I, Branched-Chain α-Ketoacid Dehydrogenase Kinase Inhibitor I
  • References Tso, S.C., et al. 2013. Proc. Natl. Acad. Sci. USA 110, 9728.
  • Ozcan, U., et al. 2006. Science 313, 1137.
  • Carducci, M.A., et al. 2001. Clin. Cancer Res. 7, 3047.
  • Rubenstein, R.C. and Zeitlin, P.L. 2000. Am.J. Physiol. Cell. Physiol. 278, C259.
  • Lea, M.A., et al. 1999. Anticancer Res. 19, 1971.
  • Miller, A.C., et al. 1997. Int. J. Radiat. Biol. 72, 211.
  • Rubenstein, R.C., et al. 1997. J. Clin. Invest. 100, 2457.
  • Pineau, T., et al. 1996. Biochem. Pharmacol. 52, 659.
  • Collins, A.F., et al. 1995. Blood 85, 43.
  • Lea, M.A., et al. 1995. Anticancer Res. 15, 879.
  • Figg, W.D., et al. 1994. Anticancer Drugs 5, 336.
  • Liu, L., et al. 1994. J. Invest. Dermatol. 103, 335.
  • CAS number 1716-12-7
  • ATP Competitive N
  • Form White to slightly yellow solid
  • Hill Formula CHONa
  • Chemical formula CHONa
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Application Sodium 4-Phenylbutyrate, CAS 1716-12-7, is a novel anti-neoplastic agent and transcriptional regulator. Also acts as an inducer of tumor cytostasis and differentiation.
  • Primary Target Anti-neoplastic agent
  • Purity ≥ 98% by Assay
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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