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Merck - 5677-5GM - Spermine, Tetrahydrochloride | CAS 306-67-2 | Calbiochem | 5GM

  • MFR SKU: 5677-5GM
  • ITEM #: 3018129
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ITEM #: 3018129
Spermine, Tetrahydrochloride^ Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors. Purity: >=99% by titration. Soluble in water. CAS: 306-67-2. FW: 348.3. 5g white solid.
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Merck - 5677-5GM - Spermine, Tetrahydrochloride | CAS 306-67-2 | Calbiochem | 5GM

  • Item #: 3018129
  • MFR SKU: 5677-5GM
  • Overview Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Acts as an inhibitor of phospholipase Cα and an activator of phospholipase Cδ. Inhibits DNA fragmentation and morphological apoptosis. Inhibits neuronal NOS.
  • Catalogue Number 5677
  • Brand Family Calbiochem®
  • References Igarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
  • Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
  • Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
  • Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
  • Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
  • Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
  • Ask, A., et al. 1992. Cancer Lett. 66, 29.
  • Chida, N., et al. 1992. Brain Res. 593, 57.
  • Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
  • Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
  • Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
  • Shantz, L.M., et al. 1992. Biochem. J. 288, 511.
  • CAS number 306-67-2
  • Form White solid
  • Hill Formula CHN . 4HCl
  • Chemical formula CHN . 4HCl
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target phospholipase C α
  • Secondary target nNOS
  • Purity ≥ 99% by titration
  • RTECS EJ7230000
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage +15° C to +30° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot, purge with inert gas, and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C under inert gas.

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