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Merck - 5.04632.0001 - PHCCC - CAS 1161205-27-1 - Calbiochem

  • MFR SKU: 5.04632.0001
  • ITEM #: 13025411
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ITEM #: 13025411
This listing is for 10 mg Glass bottle

Merck - 5.04632.0001 - PHCCC - CAS 1161205-27-1 - Calbiochem

  • Item #: 13025411
  • MFR SKU: 5.04632.0001
  • Overview A potent positive allosteric modulator selective for mGlu 4 receptors (EC 50 = 3 µ M). Also, a less potent agonist of mGlu 6 receptors (EC 50 = 15 µ M). Biologically active admitted systematically. Often used in assessing the functional roles of mGlu 4 receptors or group III mGlu receptors in a variety of research areas, such as epileptic seizures, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease.
  • Catalogue Number 504632
  • Brand Family Calbiochem®
  • Synonyms (E)-1, 1a, 7, 7a-Tetrahydro-7-(hydroxyimino)-N-phenylcyclopropa[b]chromene-1a-carboxamide
  • References Oh, H., et al. 2013. Psychopharmacol. 1, 9.
  • Dickerson, W., 2012. Neurodegen. Diseases Manag. 2, 221.
  • Le Poul, E., et al. 2012. J. Pharmacol. & Exp. Therap. 343, 167.
  • Szczurowska, E., 2012. Physiol. Res. 61, 619.
  • Beqollari, D., et al. 2008. Eur. J. Pharmacol. 589, 4.
  • Niswender, M., et al. 2008. Mol. Pharmacol. 74, 1345.
  • Stachowicz, K., et al. 2004. Eur. J. Pharmacol. 498, 153.
  • Maj, M., et al. 2003. Neuropharmacol. 45, 895.
  • Marino, J., et al. 2003. PNAS. 100, 13668.
  • CAS number 1161205-27-1
  • Form White solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Structure formula Image
  • Primary Target mGlu receptors
  • Purity ≥ 98% by HPLC
  • Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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