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Merck - 5.04914.0001 - CNQX - CAS 115066-14-3 - Calbiochem

  • MFR SKU: 5.04914.0001
  • ITEM #: 13025447
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ITEM #: 13025447
This listing is for 10 mg Glass bottle

Merck - 5.04914.0001 - CNQX - CAS 115066-14-3 - Calbiochem

  • Item #: 13025447
  • MFR SKU: 5.04914.0001
  • Overview A potent and competitive antagonist for AMPA/kainate receptors (K i = 0.6 - 2.11 µ M for GluA1-4 and K i = 1.3-5.3 µ M for different subtypes of Kainate receptors) and a negative allosteric modulator at NMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions.
  • Please note that the molecular weight for this compound is batch-specific due to variable water content.
  • Catalogue Number 504914
  • Brand Family Calbiochem®
  • Synonyms 6-Cyano-7-nitroquinoxaline-2, 3-dione, 6-Cyano-2, 3-dihydroxy-7-nitro-quinoxaline
  • References Lee, S., et al. 2010. J. Neurophysiol. 103, 1728.
  • King, A., et al. 1992. Br. J. Pharmacol. 107, 375.
  • Long, S. et al. 1990. Br. J. Pharmacol. 100, 850.Harris, K., et al. 1989. Brain Res. 5, 185Honore, T., et al. 1988. Science. 241, 701.Birch, P., et al. 1988. Eur. J. Pharmacol. 156, 177.
  • CAS number 115066-14-3
  • Form Off-white to yellow solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target AMPA i $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target K i " value=" Biological Information"
  • br> Primary Target K<sub>i</sub> 0.6 – 2.11 → M for GluA1 – 4 and Ki
  • Secondary target Kainate
  • Purity ≥ 99% by HPLC
  • Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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