Image is an illustration, may not reflect the exact product sold.

Merck - 5.05017.0001 - UBP310 - CAS 902464-46-4 - Calbiochem

Name: Merck - 5.05017.0001 - UBP310 - CAS 902464-46-4 - Calbiochem
SKU: 5.05017.0001
Price: 290.0 USD
Availability: InStock

$290.00

Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 13025456
This listing is for 10 mg Glass bottle

Overview A potent antagonist highly selective for GluK1 (K b = 10 nM), GluK3 (IC 50 = 23 nM), and GluK1/K5 (K b = 8 nM) subtype kainate receptors. Does not interact with GluK2 and GluK2/K5 receptors. Low affinity to AMPA receptors (K d = 83 µ M). Does not interact with mGluR1 or NMDA receptors at concentration less than 10 µ M. Often used in studying neuronal excitability and synaptic plasticity.
Catalogue Number 505017
Brand Family Calbiochem®
Synonyms GluK1/GluK3 antagonist, UBP310, (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione, UBP-310, UBP 310
References Pinheiro, S., et al. 2013. Cereb. Cort. 23, 323.
Atlason, T., et al. 2010. Mol. Pharmacol. 78, 1036.
Perrais, D., et al. 2009. Neuropharmacol. 56, 131.
Dolman, P., et al. 2007. J. Med. Chem. 50, 1558.
Mayer, L., et al. 2006. J. Neurosci. 26, 2852.
CAS number 902464-46-4
Form White solid

Hill Formula CHNOS
Chemical formula CHNOS
Structure formula Image
Quality Level MQ100
Primary Target GluK1 i $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target K i " value=" Biological Information"

br> Primary Target K<sub>i</sub> 10nM
Secondary target Gluk3
Purity ≥ 98% by HPLC
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2° C to +8° C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

Add Question

Tell us about your personal experience

Write a review