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Merck - 5.31492.0001 - 12/15-Lipoxygenase Inhibitor, ML351 - Calbiochem

  • MFR SKU: 5.31492.0001
  • ITEM #: 17954167
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$342.50
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ITEM #: 17954167
A cell-permeable, highly potent, selective, active site directed, mixed type inhibitor of lipoxygenase-12/15 (IC50 = 200 nM for human).
This listing is for 10 mg Glass bottle

Merck - 5.31492.0001 - 12/15-Lipoxygenase Inhibitor, ML351 - Calbiochem

  • Item #: 17954167
  • MFR SKU: 5.31492.0001
  • Overview A cell-permeable, non-toxic naphthyl-oxazole compound that acts as a highly potent, selective, active site directed, mixed type inhibitor of lipoxygenase-12/15 (IC 50 = 200 nM for human).
  • The inhibition appears to be non-reductive and reversible in nature.
  • Displays excellent selectivity over 5-LOX (IC 50 > 50 µ M), 12-LOX (IC 50 > 100 µ M), and 15-LOX (IC 50 > 100 µ M) and does not affect the activity of COX-1 and -2 in any significant manner (

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