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Merck - 616387-250MG - Nalpha-Tosyl-Phe Chloromethyl Ketone | CAS 402-71-1 | Calbiochem | 250MG

  • MFR SKU: 616387-250MG
  • ITEM #: 3441986
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ITEM #: 3441986
Na-Tosyl-Phe Chloromethyl Ketone^ Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. CAS: 402-71-1. Purity: >=99% by TLC. Soluble in ethanol or methanol. FW: 351.5. 250mg white solid.
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Merck - 616387-250MG - Nalpha-Tosyl-Phe Chloromethyl Ketone | CAS 402-71-1 | Calbiochem | 250MG

  • Item #: 3441986
  • MFR SKU: 616387-250MG
  • Overview
  • This product has been discontinued.
  • Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC 50 = 20 µ M).
  • Catalogue Number 616387
  • Brand Family Calbiochem®
  • Synonyms TPCK
  • References Fearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
  • Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
  • Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
  • Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
  • Nierodzik, M.L., et al. 1991. J. Clin. Invest. 87, 229.
  • Wilson, W.E., et al. 1989. J. Biol. Chem . 264, 17777.
  • CAS number 402-71-1
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHClNOS
  • Chemical formula CHClNOS
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target chymotrypsin activity in preparations 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> EC50 = 20 µ M in blocking the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides.
  • Purity ≥ 98% by TLC
  • Cell permeable N
  • RTECS XT5613500
  • R Phrase R: 41
  • Risk of serious damage to eyes.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage +2° C to +8° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, store in the refrigerator (4° C). Stock solutions are stable for up to 4 months at 4° C.

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