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Merck - 654380-10MG - Tunicamycin, Streptomyces lysosuperficus - CAS 11089-65-9 - Calbiochem

MFR SKU: 654380-10MG

ITEM #: 3441700

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ITEM #: 3441700
Tunicamycin, Streptomyces lysosuperficus^ Tan solid. A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against gram-positive bacteria, yeasts, fungi, and viruses. 10mg.
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Merck - 654380-10MG - Tunicamycin, <i>Streptomyces</i> <i>lysosuperficus</i> - CAS 11089-65-9 - Calbiochem

Item #: 3441700

MFR SKU: 654380-10MG

Technical Specs

Overview A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca 2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570 ).
Catalogue Number 654380
Brand Family Calbiochem®
References Tordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
Price, B.D., et al. 1992. J. Cell Physiol. 152, 545.
CAS number 11089-65-9
Form White to off-white solid
Hill Formula CHNO
Chemical formula CHNO
Reconstitution Aqueous solutions can be prepared from stock solutions in DMSO by diluting with HO at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
Structure formula Image
Quality Level MQ200
Primary Target N-linked glycosylation
Secondary target thrombin-induced Ca 2+ mobilization in cells

Purity ≥ 98% by HPLC (A+B+C+D)
RTECS YO7980200
R Phrase R: 26/27/28-60-61
Very toxic by inhalation, in contact with skin and if swallowed.
May impair fertility.
May cause harm to the unborn child.
S Phrase S: 22-36/37/39-45
Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15° C to +30° C
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 2 weeks at -20° C.

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