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Merck - ABN2191 - ABN2191, Anti-Calretinin from rabbit, purified by affinity chromatography

  • MFR SKU: ABN2191
  • ITEM #: 11556131
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ITEM #: 11556131
Calretinin (UniProt: P47728; also known as CR) is encoded by the Calb2 gene (Gene ID: 117059) in rat. Calretinin belongs to the calbindin protein family and acts as a calcium-binding protein. It is e x pressed in both central and peripheral nervous system and is found abundantly in auditory neurons. It is involved in regulating cytosolic calcium ion concentrations and has multiple calcium-binding domains known as EF-hands. Its e x pression is shown to be regulated at the level of transcription by...
ITEM #: 11556131
Calretinin (UniProt: P47728; also known as CR) is encoded by the Calb2 gene (Gene ID: 117059) in rat. Calretinin belongs to the calbindin protein family and acts as a calcium-binding protein. It is e x pressed in both central and peripheral nervous system and is found abundantly in auditory neurons. It is involved in regulating cytosolic calcium ion concentrations and has multiple calcium-binding domains known as EF-hands. Its e x pression is shown to be regulated at the level of transcription by nuclear respiratory factor 1 (NRF-1) and E2F2 transcription factors. In rat striatum calretinin neurons form a distinct subset of medium-sized (7 20 microm), aspiny, GABAergic interneurons. Calretinin can also serve as an important differential diagnostic tool for cystic and solid ameloblastic tumors. (Ref.: Petryszyn, S., et al. (2017). J. Neural Transm. doi: 10.1007/s00702-017-1687; Kresoja-Rakic, J., et al. (2017). Front. Genet. doi: 10.3389/ ).
Synonyms: CR
Application: Western Blotting Analysis: A 1:500 dilution from a representative lot detected Calretinin in rat brain tissue Analysis: A 1:1, 000 dilution from a representative lot detected Calretinin in human cerebral corte x and rat cerebellum tissue sections.
Other Notes: Concentration: Please refer to lot specific datasheet.
ABN2191, Anti-Calretinin from rabbit, purified by affinity chromatography
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Merck - ABN2191 - ABN2191, Anti-Calretinin from rabbit, purified by affinity chromatography

  • Item #: 11556131
  • MFR SKU: ABN2191

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