Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - AG252 - GAD, control peptide for AB1511; 50 µg

  • MFR SKU: AG252
  • ITEM #: 11556982
    • 0 out of 5 stars
    • 5 Star
      0 %
    • 4 Star
      0 %
    • 3 Star
      0 %
    • 2 Star
      0 %
    • 1 Star
      0 %
  • 0 Reviews / 0 Questions
$488.00

  • Please complete this captcha to continue

Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

  • Please complete this captcha to continue

    * Please log into your account to avoid entering this information every time.


ITEM #: 11556982
80%
Entrez Gene Number
  • NM_000818.1

Entrez Gene Summary This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent...
ITEM #: 11556982
80%
Entrez Gene Number
  • NM_000818.1

Entrez Gene Summary This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome.
Gene Symbol
  • GAD2
  • MGC161607
  • GAD65
  • MGC161605
  • GAD-65
  • EC 4.1.1.15

UniProt Number
  • Q05329

UniProt Summary FUNCTION: SwissProt: Q05329 # Catalyzes the production of GABA.
COFACTOR: Pyridoxal phosphate.
SIZE: 585 amino acids; 65411 Da
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Cytoplasmic vesicle. Cell junction, synapse, presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
PTM: Phosphorylated; which does not affect kinetic parameters or subcellular location. & Palmitoylated; which is required for presynaptic clustering.
SIMILARITY: SwissProt: Q05329 ## Belongs to the group II decarboxylase family.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Conditions Long term storage at -20°C in a sealed container with desiccant for up to 12 months after date of receipt.
Material Size 50 µg
Read More >>

Merck - AG252 - GAD, control peptide for AB1511; 50 µg

  • Item #: 11556982
  • MFR SKU: AG252
Questions & Answers

There are no questions about this product yet. Be the first to ask a question.

Add Question
0 Customer Ratings & Reviews
0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Write a review

Recently Viewed Items