Merck - MCD8MAG48K-PX15 - MCD8MAG48K-PX15, MILLIPLEX(R) Mouse CD8+ T Cell Magnetic Bead Panel Premixed 15 Plex - Immunology Multiplex Assay Inflammation/Immunology Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis

ITEM #: 11567540
CD8+ T cells (also known as cytoto x ic T cells, cytolytic T cells and killer T cells) belong to a sub-group of T cells capable of inducing the death of infected somatic or tumor cells. T cells that bind weakly to Major Histocompatibility Comple x (MHC) self-antigens are positively selected into single-positive CD4+ or CD8+ T cells in the thymus. Those CD8+ T cells that survive and mature after activation become cytoto x ic cells, e x pressing T-cell receptors (TCRs) capable of recognizing specific antigenic peptides bound to Class I MHC molecules and the glycoprotein CD8. Affinity between the CD8 protein and the MHC molecule helps to keep the cytoto x ic T cell and target closely bound during antigen specific activation. Once activated, CD8+ T cells are generally classified as having a predefined cytoto x ic role within the immune system and undergo IL-2 induced clonal e x pansion, which increases the number of cells specific for the target antigen. The CD8+ T cells then travel throughout the body in search of antigen-positive somatic/tumor cells. The MILLIPLEX(R) Mouse CD8+ T Cell Bead Panel enables you to focus on the therapeutic potential of Mouse CD8+ T Cell analytes. Coupled with the Lumine x (R) x MAP(R) platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiple x detection of several analytes simultaneously, which can dramatically improve productivity. The MILLIPLEX(R) Mouse CD8+ T Cell Bead Panel is the most versatile system available for Mouse CD8+ T Cell research. This [MILLIPLEX(R) kit offers you the ability to:
•Select a 15-ple x premi x ed option or
•Choose any combination of analytes from our panel of 15 analytes to design a custom kit that better meets your needs.
•A convenient "all-in-one" bo x format gives you the assurance that you will have all the necessary reagents you need to run your assay. Panel Type: Cytokines/Chemokines
Application:
•Analytes: sCD137, sFas, sFAS ligand, GM-CSF, Granzyme B, IFNgamma, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, MIP-1beta, RANTES, TNF-alpha
•Recommended Sample type: serum, plasma and cell culture samples
•Recommended Sample dilution: neat
•Assay Run Time: one day or overnight
•Research Category: Inflammation & Immunology
: x MAP is a registered trademark of Lumine x Corp
Other Notes: Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.
MCD8MAG48K-PX15, MILLIPLEX(R) Mouse CD8+ T Cell Magnetic Bead Panel Premixed 15 Plex - Immunology Multiplex Assay Inflammation/Immunology Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple cytokine and c
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