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Merck - N0142-100UL - Monoclonal Anti-Neurofilament 200 (Phos. and Non-Phos.) antibody 100UL

  • MFR SKU: N0142-100UL
  • ITEM #: 13105952
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ITEM #: 13105952
Neurofilaments are composed of three subunits, namely NEFL (light), NEFM (medium) and NEFH (heavy). NEFH (neurofilament heavy) gene encodes the most important neuron-specific intermediate filament of cytoskeleton in myelinated a x ons. This gene is mapped to human chromosome 22q12.2.Monoclonal Anti-Neurofilament 200 (phosphorylated and non-phosphorylated) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
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ITEM #: 13105952
Neurofilaments are composed of three subunits, namely NEFL (light), NEFM (medium) and NEFH (heavy). NEFH (neurofilament heavy) gene encodes the most important neuron-specific intermediate filament of cytoskeleton in myelinated a x ons. This gene is mapped to human chromosome 22q12.2.Monoclonal Anti-Neurofilament 200 (phosphorylated and non-phosphorylated) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
MDL Number: MFCD00164708
Storage: -20C
Application: Monoclonal Anti-Neurofilament 200 (Phos. and Non-Phos.) antibody has been used in immunohistochemistry and western blotting.
Biochem Physiol Actions: The heavy polypeptide neurofilament encoded by neurofilament heavy chain (NEFH) gene participates in the maintenance of cytoskeleton and a x onal architecture in the pro x imal a x onal region of spinal motoneurons. Mutations in the NEFH gene has a key role in the pathogenesis of sporadic amyotrophic lateral sclerosis (ALS). NEFH gene is also identified to generate autosomal dominant a x onal Charcot-Marie-tooth disease (CMT2cc).
Monoclonal Anti-Neurofilament 200 (Phos. and Non-Phos.) antibody 100UL
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Merck - N0142-100UL - Monoclonal Anti-Neurofilament 200 (Phos. and Non-Phos.) antibody 100UL

  • Item #: 13105952
  • MFR SKU: N0142-100UL

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