Merck - SCC008 - SCC008, ReNcell VM Human Neural Progenitor Cell LIne ReNcell VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.

ITEM #: 11569508
Re. Ncell VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons and glial cells. Re. Ncell VM was derived from the ventral mesencephalon region of human fetal brain. Immortalized by retroviral transduction with the v-myc oncogene, this cell line grows rapidly as a monolayer on laminin with a doubling time of 20-30 hours. Karyotype analyses indicate that the Re. Ncell VM retains a normal diploid karyotype in culture even after prolonged passage (>45 passages). Re. Ncell VM was developed by the Re. Neuron Group plc, a biotech company that specializes in using human somatic stem cells for therapeutics. In e x periments performed by the Re. Neuron Group plc, Re. Ncell VM can be differentiated in vitro to a high level of human dopaminergic neurons. Neurons differentiated from Re. Ncell VM have furthermore been shown to be electophysiologically active. Re. Ncell VM may be used for a variety of research applications such as studies of neuroto x icity, neurogenesis, electrophysiology, neurotransmitter and receptor functions. Re. Ncell VM cells have been obtained in a legal and ethical manner, compliant with current local informed consent Now Used in a 3D Cell Model of Alzheimer's Disease! Tanzi, R and Kim, DY et. al. A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 2014 Nov 13;515(7526):274-8.(Published in Nature)
Application: Research Category. Stem Cell Research
: CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
SCC008, Re. Ncell VM Human Neural Progenitor Cell LIne Re. Ncell VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.
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