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Merck - SCC111 - SCC111, R-Spondin1 expressing 293T Cell Line The R-Spondin1-Expressing 293T cell line produces RSPO1, a critical protein used to establish 3D organoid cultures from stomach, small intestine, colon, pancreas, and liver sources.

  • MFR SKU: SCC111
  • ITEM #: 11591582
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ITEM #: 11591582
RSPO1 is an intestinal growth factor that works as a potent activator of the Wnt/beta-catenin signaling pathway by binding to leucine-rich repeat-containing G protein-coupled receptors (LGRs), which are e x pressed in tissue stem cells. RSPO1 also binds to the transmembrane E3 ubiquitin ligases RNF43 and ZNRF3 and triggers their internalization, thereby potentiating Wnt 293T cell line is stably transfected to e x press mouse R-spondin1 protein tagged with N-terminus HA epitope tag and C-terminus...
ITEM #: 11591582
RSPO1 is an intestinal growth factor that works as a potent activator of the Wnt/beta-catenin signaling pathway by binding to leucine-rich repeat-containing G protein-coupled receptors (LGRs), which are e x pressed in tissue stem cells. RSPO1 also binds to the transmembrane E3 ubiquitin ligases RNF43 and ZNRF3 and triggers their internalization, thereby potentiating Wnt 293T cell line is stably transfected to e x press mouse R-spondin1 protein tagged with N-terminus HA epitope tag and C-terminus mouse IgG2alpha Fc region. R-Spondin1 e x pressing 293T cell line can be used to produce either purified Rspo1 or Rspo1 conditioned media. The FC region and HA tags enable ease of purification and characterization. Cell line is not the published cell line from the Kuo lab, but rather a related cell line developed in the same lab using the reference protocol.
Application: This product is intended for sale and sold solely for internal non-commercial research use per the terms of the “Restricted Use Agreement” as detailed in the product documentation. For information regarding any other uses, please contact licensing@ .
SCC111, R-Spondin1 expressing 293T Cell Line The R-Spondin1-Expressing 293T cell line produces RSPO1, a critical protein used to establish 3D organoid cultures from stomach, small intestine, colon, pancreas, and liver sources.
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Merck - SCC111 - SCC111, R-Spondin1 expressing 293T Cell Line The R-Spondin1-Expressing 293T cell line produces RSPO1, a critical protein used to establish 3D organoid cultures from stomach, small intestine, colon, pancreas, and liver sources.

  • Item #: 11591582
  • MFR SKU: SCC111

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