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Merck - SCC117 - SCC117, Histone H2B-GFP expressing HeLa Cell Line The Histone H2B-GFP expressing HeLa cell line is a useful cell model for imaging and analysis of chromosome dynamics.

  • MFR SKU: SCC117
  • ITEM #: 11569547
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ITEM #: 11569547
Chromatin, the higher order structure of DNA, proteins and RNA, constitutes the majority of the nucleus of eukaryotic cells. Changes in chromatin structure are the essence of many essential nuclear processes, including transcription, meiosis, mitosis, and apoptosis. The nucleosome represents the primary building block of chromatin and it comprises an octomer of four core histone proteins (H2A, H2B, H3 and H4). HeLa cells e x pressing green fluorescent protein fused histone H2B (H2B-GFP) have been...
ITEM #: 11569547
Chromatin, the higher order structure of DNA, proteins and RNA, constitutes the majority of the nucleus of eukaryotic cells. Changes in chromatin structure are the essence of many essential nuclear processes, including transcription, meiosis, mitosis, and apoptosis. The nucleosome represents the primary building block of chromatin and it comprises an octomer of four core histone proteins (H2A, H2B, H3 and H4). HeLa cells e x pressing green fluorescent protein fused histone H2B (H2B-GFP) have been widely used to visualize the dynamics of chromosomal architecture in living cells during various processes. In addition to studying normal mitosis, histone H2B-GFP has been utilized for imaging the distinctive clustering behavior of double minute chromosomes (DMs) in cancer cells during mitosis, which contributes to their asymmetric distribution to daughter cells. Monitoring histone H2B-GFP also permits continuous analysis of chromosomal degradation during apoptosis.
Synonyms: Histone H2B
Application: This product is intended for sale and sold solely for internal non-commercial research use per the terms of the “Restricted Use Agreement” as detailed in the product documentation. For information regarding any other uses, please contact licensing@ .
SCC117, Histone H2B-GFP expressing HeLa Cell Line The Histone H2B-GFP expressing HeLa cell line is a useful cell model for imaging and analysis of chromosome dynamics.
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Merck - SCC117 - SCC117, Histone H2B-GFP expressing HeLa Cell Line The Histone H2B-GFP expressing HeLa cell line is a useful cell model for imaging and analysis of chromosome dynamics.

  • Item #: 11569547
  • MFR SKU: SCC117

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