Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - SCC148 - SCC148, MB49 Mouse Bladder Carcinoma Cell Line MB49 mouse urothelial carcinoma cell line is widely used as an in vitro and in vivo model of bladder cancer.

  • MFR SKU: SCC148
  • ITEM #: 11569557
    • 0 out of 5 stars
    • 5 Star
      0 %
    • 4 Star
      0 %
    • 3 Star
      0 %
    • 2 Star
      0 %
    • 1 Star
      0 %
  • 0 Reviews / 0 Questions
$1,596.44

  • Please complete this captcha to continue

Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

  • Please complete this captcha to continue

    * Please log into your account to avoid entering this information every time.


ITEM #: 11569557
MB49 cells are derived from C57BL/Icrf-a' mouse bladder epithelial cells that were transformed by a single 24-hour treatment with the chemical carcinogen 7, 12-dimethylbenz[a]anthracene (DMBA) on the second day of a long term primary culture . Transformed cells transplanted into syngeneic mice were shown to generate carcinomas . While of male origin, karyotype analyses indicate the loss of the Y chromosome in 100% of the cells analyzed . This abnormality is a frequent early event in human bladder...
ITEM #: 11569557
MB49 cells are derived from C57BL/Icrf-a' mouse bladder epithelial cells that were transformed by a single 24-hour treatment with the chemical carcinogen 7, 12-dimethylbenz[a]anthracene (DMBA) on the second day of a long term primary culture . Transformed cells transplanted into syngeneic mice were shown to generate carcinomas . While of male origin, karyotype analyses indicate the loss of the Y chromosome in 100% of the cells analyzed . This abnormality is a frequent early event in human bladder cancer. A recent study indicates that MB49 cells recapitulate key features of se x differences in bladder tumor growth . MB49 implantation in mice resulted in significantly larger tumors in males than females. In the presence of dihydrotestosterone, MB49 cells e x hibited enhanced proliferation in a dose-dependent manner. In contrast, MB49 cells were unresponsive to the pregnancy hormone, human chorionic gonadotrophin (hCG) . MB49 cells e x hibit low to no e x pression of MHC-Class I and II molecules . However, upon e x posure to IFN-???, the e x pressions of MHC Class I and II are significantly upregulated .
Synonyms: MB-49
SCC148, MB49 Mouse Bladder Carcinoma Cell Line MB49 mouse urothelial carcinoma cell line is widely used as an in vitro and in vivo model of bladder cancer.
This listing is for Each
Read More >>

Merck - SCC148 - SCC148, MB49 Mouse Bladder Carcinoma Cell Line MB49 mouse urothelial carcinoma cell line is widely used as an in vitro and in vivo model of bladder cancer.

  • Item #: 11569557
  • MFR SKU: SCC148
Questions & Answers

There are no questions about this product yet. Be the first to ask a question.

Add Question
0 Customer Ratings & Reviews
0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Write a review

Recently Viewed Items