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Merck - SCC201 - SCC201, LOX-IMVI Human Melanoma Cell Line LOX-IMVI human melanoma cell line is an excellent model for probing mechanisms of metastasis and for evaluation of chemotherapies.

  • MFR SKU: SCC201
  • ITEM #: 17972203
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ITEM #: 17972203
The LOX-IMVI human melanoma cell line is widely used as an in vitro model system to study tumor metastasis and to test for chemosensitivity to potential anti-cancer compounds. LOX-IMVI cells e x hibit a tendency to form lung metastases in nude mice independent of the inoculation site , and mortality of e x perimental animals is observed within 3-5 weeks of LOX-IMVI cell injection . LOX-IMVI cells are genetically characterized by lack of the Y chromosome and trisomy 7 , and are heterozygous for the...
ITEM #: 17972203
The LOX-IMVI human melanoma cell line is widely used as an in vitro model system to study tumor metastasis and to test for chemosensitivity to potential anti-cancer compounds. LOX-IMVI cells e x hibit a tendency to form lung metastases in nude mice independent of the inoculation site , and mortality of e x perimental animals is observed within 3-5 weeks of LOX-IMVI cell injection . LOX-IMVI cells are genetically characterized by lack of the Y chromosome and trisomy 7 , and are heterozygous for the BRAF V600E melanoma driver mutation . LOX-IMVI cells are amelanotic and e x press the human melanoma marker GD3 ganglioside, a factor in metastatic potential of malignant melanoma . Source: The LOX-IMVI human melanoma cell line was established from a subcutaneous x enograft in nude mice from a lymph node metastasis of a 58-year-old Caucasian male patient with malignant amelanotic melanoma .
Synonyms: LOX/IMVI, LOX IMVI, LOXIM-VI, LOXIMVI
Application: This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@ .
SCC201, LOX-IMVI Human Melanoma Cell Line LOX-IMVI human melanoma cell line is an excellent model for probing mechanisms of metastasis and for evaluation of chemotherapies.
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Merck - SCC201 - SCC201, LOX-IMVI Human Melanoma Cell Line LOX-IMVI human melanoma cell line is an excellent model for probing mechanisms of metastasis and for evaluation of chemotherapies.

  • Item #: 17972203
  • MFR SKU: SCC201

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