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Merck - SCC256 - SCC256, BPH-1 Human Benign Prostatic Hyperplasia Cell Line The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.

  • MFR SKU: SCC256
  • ITEM #: 22551856
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ITEM #: 22551856
BPH-1 is an immortalized benign prostatic hyperplasia cell line that is a highly cited human model for prostate growth and physiology. Compared to prostate cancer cell lines, BPH-1 cells e x pressed increased levels of estradiol (E2) and aromatase, factors that have been implicated in BPH progression (2). BPH-1 cells share the cytokeratin profile of luminal epithelial cells and do not e x press androgen receptor or prostate-specific antigen (PSA) (3). BPH-1 cells e x press the proto-oncogene p53...
ITEM #: 22551856
BPH-1 is an immortalized benign prostatic hyperplasia cell line that is a highly cited human model for prostate growth and physiology. Compared to prostate cancer cell lines, BPH-1 cells e x pressed increased levels of estradiol (E2) and aromatase, factors that have been implicated in BPH progression (2). BPH-1 cells share the cytokeratin profile of luminal epithelial cells and do not e x press androgen receptor or prostate-specific antigen (PSA) (3). BPH-1 cells e x press the proto-oncogene p53 and harbor several chromosomal structural rearrangements but are non-tumorigenic in nude mice (3). Source:The BPH-1 cell line was established from primary prostatic tissue from a 68-year-old patient and the cell line was immortalized with Simian virus 40 (SV40) large T antigen (3). BPH-1 cells contain a neomycin resistance cassette and are resistant to G418.
SCC256, BPH-1 Human Benign Prostatic Hyperplasia Cell Line The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.
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Merck - SCC256 - SCC256, BPH-1 Human Benign Prostatic Hyperplasia Cell Line The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.

  • Item #: 22551856
  • MFR SKU: SCC256

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