Merck - SCT037 - SCT037, BioTracker Far-red Labile Fe2+ Dye Live Cell imaging probe for labile ferrous (Fe2+) ions, localizing inside endoplasmic reticulum (ER). Also suitable for flow cytometry.

ITEM #: 22551881
Iron, the most abundant transition metal in our bodies, is involved in a number of biologically important processes such as respiration, o x ygen transport, and energy production in collaboration with o x ygen. In living cells, iron e x ists mainly as ferrous (Fe2+) and ferric (Fe3+) ionic forms. As a major contributor to o x idative damage of cells, Fe2+ is implicated in serious diseases such as cancers and neurodegenerative disorders, because of its ability to produce harmful reactive o x ygen species via contact with o x ygen, supero x ide, and hydrogen pero x ide (H2O2).Bio. Tracker far-red labile Fe2+ dye is a fluorescent probe that specifically detects labile iron (II) ions (Fe2+). This probe is designed to selectively react with only Fe2+ separately from other metal ions and irreversibly turns into a far-red fluorescent substance. It mainly localizes inside endoplasmic reticulum (ER) and/or golgi bodies. It can also be used with a flow cytometer equipped with a red laser. FerroFar. Red shows almost no cytoto x icity at concentrations up to 100 muM (~20 times that of generally used concentrations).This product is same as FerroFarRedTM (GC903-01) from Goryo Chemical, Properties:Absorbance (ma x ): 646nm. Emission (ma x ): 662nm (Far-red)Research Category:Live Cell Dye
SCT037, Bio. Tracker Far-red Labile Fe2+ Dye Live Cell imaging probe for labile ferrous (Fe2+) ions, localizing inside endoplasmic reticulum (ER). Also suitable for flow cytometry.
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