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Merck - SCT065 - SCT065, Green-AlDeSense ALDH1A1 Live Cell Dye ALDH1A1 isoform specific live cell dye which labels cancer stem cells for fluorescent microscopy, flow cytometry and in vivo applications.

  • MFR SKU: SCT065
  • ITEM #: 22551889
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ITEM #: 22551889
Cancer stem cells (CSCs) have an increased capacity to activate antiapoptotic/prosurvival pathways as well as overe x pressing ATP-binding cassette transporters which act as potent efflu x pumps for potential chemotherapeutics. Aldehyde dehydrogenases (ALDH), in particular the ALDH1A1 isoform, is believed to be a reliable marker of CSCs across many cancer types, including prostate, lung, breast, esophageal, and ovarian cancers. ALDH1A1 is associated with increased chemotherapy resistance and poor...
ITEM #: 22551889
Cancer stem cells (CSCs) have an increased capacity to activate antiapoptotic/prosurvival pathways as well as overe x pressing ATP-binding cassette transporters which act as potent efflu x pumps for potential chemotherapeutics. Aldehyde dehydrogenases (ALDH), in particular the ALDH1A1 isoform, is believed to be a reliable marker of CSCs across many cancer types, including prostate, lung, breast, esophageal, and ovarian cancers. ALDH1A1 is associated with increased chemotherapy resistance and poor clinical outcome and is an established stem cell methods to identify ALDH in living cells are limited by cross-reactivity with several ALDH isoforms producing difficulties in data analysis and prognosis. Chan, et al. have created a ALDH1A1 isoform specific live cell dye termed Green-AlDeSense which labels cancer stem cells and e x hibits a 20-fold fluorescent enhancement when bound to ALDH1A1. The dye identifies ALDH1A1 positive CSCs using live cell imaging, flow cytometry and in vivo Properties: absma x : 496 nm, emma x : 516 nm.
SCT065, Green-AlDeSense ALDH1A1 Live Cell Dye ALDH1A1 isoform specific live cell dye which labels cancer stem cells for fluorescent microscopy, flow cytometry and in vivo applications.
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Merck - SCT065 - SCT065, Green-AlDeSense ALDH1A1 Live Cell Dye ALDH1A1 isoform specific live cell dye which labels cancer stem cells for fluorescent microscopy, flow cytometry and in vivo applications.

  • Item #: 22551889
  • MFR SKU: SCT065

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