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MP Biomedicals - 0219454405 - POLY-L-LYSINE HYDROBROMIDE 70000MW 5MG (Each)

  • MFR SKU: 0219454405
  • ITEM #: 13276246
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ITEM #: 13276246
Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein.
Poly-L-lysine is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. Can be used as a coating substrate since poly-lysine is a nonspecific...
ITEM #: 13276246
Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein.
Poly-L-lysine is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. Can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. Other uses for poly-lysine have been reported as follows:
  • Conjugation to methotre x ate for increased drug transport
  • Microencapsulation of islets
  • Use in simple reproducible procedure for chromosomal preparations from a variety of tissues
  • Immobilation of living cells in biocompatible semipermeable microcapsules
  • Poly-L-Lysine In the preparation of polycationic beads
  • Conjugation to albumin and horseradish pero x idase to enhance cellular uptake

  • Typically, the effective coating solution concentration for culture dishes will be 0.3 to 0.5% and for histology slides at 0.1%. Recommended as a cell culture substratum when using 0.5 mL of a 0.1 mg/mL solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
    Pkg. Type : Amber Glass Bottle
    This listing is for Each
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MP Biomedicals - 0219454405 - POLY-L-LYSINE HYDROBROMIDE 70000MW 5MG (Each)

  • Item #: 13276246
  • MFR SKU: 0219454405

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