OZ Biosciences - LC50000 - Dmnpe- Caged Luciferin Salt, 50 Mg

  • MFR SKU: LC50000
  • ITEM #: 17057849
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$830.35
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ITEM #: 17057849
The cell permeable DMNPE-caged Luciferin is as a bioluminescent luciferase substrate used to measure intracellular functions since it readily crosses cell membranes. It is a D-luciferin ester analogue of luciferin.
Once the caged luciferin is inside the cells, active luciferin can be released by the action of endogenous intracellular esterases or by a flash of UV light.
This allows for a more efficient delivery of luciferin into intact living cells, improved sensitivity analysis of in...
ITEM #: 17057849
The cell permeable DMNPE-caged Luciferin is as a bioluminescent luciferase substrate used to measure intracellular functions since it readily crosses cell membranes. It is a D-luciferin ester analogue of luciferin.
Once the caged luciferin is inside the cells, active luciferin can be released by the action of endogenous intracellular esterases or by a flash of UV light.
This allows for a more efficient delivery of luciferin into intact living cells, improved sensitivity analysis of in vivo luciferase assays, and a long-term measurement of luciferase activity since hydrolysis by esterases allows a continuous supply of active Luciferin. DMNPE-caged luciferin appears a good alternative to D-Luciferin classically used to measure luciferase activity in live cells. Indeed, the difficulty to deliver D-Luciferin into living cells renders in vivo quantification limited to a certain e x tent - for e x ample, permeability issues at neutral pH.
  • High purity
  • Cell permeable: efficient luciferin delivery into intact cells even at neutral pH
  • Ideal for in vivo applications
  • Induces prolonged release of luciferin by the action of cells’ esterases
  • Allows to follow changes in gene e x pression in live cells
  • Suitable for in vitro e x periments

Dmnpe- Caged Luciferin Salt, 50 Mg
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OZ Biosciences - LC50000 - Dmnpe- Caged Luciferin Salt, 50 Mg

  • Item #: 17057849
  • MFR SKU: LC50000

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